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School of Public Health and Health Professions

Health Information > Heart Disease

What is Heart Disease

Definition

This information item focuses upon heart disease resulting from atherosclerotic changes - the changes that occur because of the build up of plaques or fatty streaks on the interior walls of the blood vessels that supply oxygenated blood to the heart muscle. This is also known as coronary artery disease.

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Description

The heart is a muscular pump in the chest. Throughout life it beats continuously and rhythmically to send blood to the lungs and the rest of the body.

The normal heart weighs approximately 10 1/2 ounces and is about the size of your fist. It beats 60 to 120 times a minute, depending on whether you are excited or resting.

The average blood cell makes a round trip through the body's arteries and veins every 60 seconds, and can hit speeds of up to 10 mph. The heart pumps your five quarts of blood around your body 500 times a day.

When the arteries become clogged with deposits made up of "bad" cholesterol, plaque, scar tissue, or calcium, the heart has a harder time circulating blood. This clogging causes a myriad of heart problems from angina pectoris (chest pain) to heart failure to a heart attack.

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Causes and Risk Factors

The primary risk factors for the development of atherosclerotic heart disease are smoking, sedentary lifestyle, hypertension, diabetes, hypercholesterolemia, and a genetic predisposition to the disease.

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